A research of omics-based biological aging clocks and their applications
10.3760/cma.j.cn112338-20240424-00215
- VernacularTitle:基于生物组学数据的衰老时钟研究及其应用
- Author:
Ziwei ZHU
1
;
Shanshan CHENG
;
Xiang CHENG
;
Weihong CHEN
;
Chaolong WANG
Author Information
1. 华中科技大学同济医学院公共卫生学院流行病与卫生统计学系,武汉 430030
- Keywords:
Aging clock;
Omics data;
Physiological age
- From:
Chinese Journal of Epidemiology
2024;45(9):1291-1301
- CountryChina
- Language:Chinese
-
Abstract:
Aging, a process of functional decline with the increase of chronological age, is a major risk factor for chronic diseases. Aging shows significant individual differences, which is influenced by both genetic and environmental factors. Accurate measurement of physiological age helps identify individuals with accelerated aging and those at high risk for chronic diseases and mortality, which would promote individual health management and precision medicine for healthy aging. In this paper, we summarize the omics-based aging clocks and discuss their current and future applications.