Exploratory study of starting age and interval of gastroscopy for different gastric mucosal lesions
10.3760/cma.j.cn112338-20240322-00147
- VernacularTitle:不同胃黏膜病变的胃镜检查起始年龄和间隔的探索研究
- Author:
Jiayi LI
1
;
Peng SHEN
;
Zhanghang ZHU
;
Mengling TANG
;
Liming SHUI
;
Yexiang SUN
;
Zhiqin JIANG
;
Hongbo LIN
;
Jianbing WANG
;
Mingjuan JIN
;
Kun CHEN
Author Information
1. 浙江大学公共卫生学院流行病与卫生统计学系，杭州 310058
- Keywords:
Gastroscopy;
Precancerous gastric lesion;
Gastric cancer;
Starting age;
Gastroscopy interval
- From:
Chinese Journal of Epidemiology
2024;45(9):1244-1250
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the current status of gastroscopy in diagnosing gastric lesions in general population, and to recommend the optimal age for the first gastroscopy and intervals for repeated gastroscopy.Methods:The gastroscopy records of residents aged 18-80 years in Yinzhou District of Ningbo, Zhejiang Province, between April 2010 and December 2021 were analyzed retrospectively. The detections of gastric lesions across different years, age and genders were described. Goodness of fit tests were applied to compare the differences in detection rates of different lesions in first-time endoscopy in different age groups and different populations. Generalized additive models were used to fit the trend of age specific gastric lesion detection rate explore the optimal age for gastroscopy. The appropriate gastroscopy intervals were determined according to the progress of the gastric lesions detected in repeated gastroscopy.Results:A total of 237 751 participants with 344 398 gastroscopy records were included in analyses. A total of 5 597 cases of chronic atrophic gastritis (CAG), 9 796 cases of intestinal metaplasia (IM), 165 cases of low-grade intraepithelial neoplasia (LGIN), 52 cases of high-grade intraepithelial neoplasia (HGIN) and 435 cases of gastric cancer were detected by the first gastroscopy. The overall detection rate of gastric lesions increased significantly in age group 45-70 years, and remained stable after 70 years old, with LGIN and HGIN showing notable increases at 50 and 55 years old, respectively. Repeated gastroscopy detected CAG, IM, LGIN, and HGIN at a higher rate compared with the first gastroscopy. Normal/superficial gastritis progressed in 3-5 years, whereas CAG or more severe lesions progressed in 1-6 years.Conclusion:Gastroscopy is recommended for general population aged 45 years and above. Furthermore, gastroscopy can be performed every 3-5 years for individuals with normal endoscopy results and once a year for patients with CAG or more severe gastric lesions.
