Processing methods and composition study of slices and decoction of Rhizoma Chuanxiong characterized by chemical composition fingerprint
10.3321/j.issn:1006-2157.2009.10.013
- VernacularTitle:以化学成分指纹图谱表征的川芎炮制及其汤剂成分研究
- Author:
Yang LIU
1
;
Ji-Chun LIANG
;
Ren-Bing SHI
;
Bin LIU
;
Yan-Yan JIANG
Author Information
1. 北京中医药大学
- Keywords:
Rhizoma Chuanxiong;
processing;
decoction;
chemical compositions;
HPLC;
fingerprint chromatogram
- From:
Journal of Beijing University of Traditional Chinese Medicine
2009;32(10):699-701
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influences of common preparation methods of slices of Rhizoma Chuanxiong on the changes of their chemical compositions by applying fingerprint chromatogram, and their dissolution characteristics in the decoction of the slices of Rhizoma Chuanxiong after exacting for different times. Methods The changes of chemical compositions of the slices, and difference between extractable compositions and original compositions of Rhizoma Chuanxiong were compared before and after the preparation by applying HPLC fingerprint chromatogram and the control and analytic method of chemical standard samples. Results The chemical compositions of the slices was not much different from original compositions after preparation. The liposoluble compositions of the slices was dissolved less in the decoction, while the most of water-soluble compositions were extracted out after extracting for three times. Conclusion When the slices of Rhizoma Chuanxiong were decocted alone, less liposoluble compositions are dissolved in decoction, which indicates that the effective material base ( chemical compositions) of the slices of Rhizoma Chuanxiong in decoction should be water-soluble compositions.