Epidemiological characteristic of viral encephalitis in children and adolescents in Henan Province, 2012-2023
10.3760/cma.j.cn112338-20231018-00235
- VernacularTitle:河南省2012-2023年儿童青少年病毒性脑炎的流行病学特征分析
- Author:
Shujie HAN
1
;
Shouhang CHEN
;
Bowen DAI
;
Yu CHEN
;
Shujuan HAN
;
Ruyu ZHANG
;
Chenyu WANG
;
Qingmei WANG
;
Jiaying ZHENG
;
Guangcai DUAN
;
Fang WANG
;
Yuefei JIN
Author Information
1. 河南省儿童医院/郑州儿童医院感染性疾病科，郑州 450018
- Keywords:
Viral encephalitis;
Enterovirus;
Coxsackie virus;
Children and adolescents
- From:
Chinese Journal of Epidemiology
2024;45(6):852-856
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the epidemiological characteristics and spatiotemporal distribution of viral encephalitis in children and adolescents in Henan Province from 2012 to 2023.Methods:The information about viral encephalitis cases from October 1, 2012 to July 26, 2023 were collected from Zhengzhou Children's Hospital (National Children's Regional Medical Center),Henan Provincial Children's Hospital for the analyses on temporal distribution the cases, the severe illness rate, age distribution, pathogen type and imaging findings of the cases.Results:A total of 6 276 cases of viral encephalitis were included in this study after excluding cases with incomplete information. The cases mainly originated from Zhengzhou (38.96%), followed by Zhoukou (9.93%), Xuchang (8.68%), Zhumadian (7.90%) and Pingdingshan (7.39%). The cases in boys accounted for 62.13% and the cases in girls accounted for 37.87%. Most cases (72.45%) occurred in age group 7-13 years. The overall rate of severe illness cases was 4.51% from 2012 to 2023. There were significant differences in severe illness cases among different areas and years ( χ2=5.33, P=0.021; χ2=48.14, P<0.001). Enteroviruses were mainly detected (31.57%), in which Coxsackie virus was predominant (58.37%). Imaging findings showed that cerebral hemisphere damage was most common in children and adolescents with viral encephalitis (54.93%). Conclusions:From 2012 to 2023, more cases of viral encephalitis occurred in boys in Henan. Children and adolescents aged 7-13 years were the main affected group. The prevention of enteroviruses infection, especially Coxsackie virus, needs to be strengthened. Special attention should be paid to the prevention of cerebral hemisphere damage after viral encephalitis diagnosis.
