Epidemiology of immune thrombocytopenia in Gansu Province, 2019-2022
10.3760/cma.j.cn112338-20231122-00308
- VernacularTitle:甘肃省2019-2022年原发性免疫性血小板减少症的流行病学特征分析
- Author:
Yongzhuo JIAO
1
;
Xiaoshu ZHANG
;
Lei WANG
;
Jing AN
;
Shuyu LIU
;
Huaqing WANG
Author Information
1. 甘肃省疾病预防控制中心免疫规划所，兰州 730000
- Keywords:
Immune thrombocytopenia;
Incidence rate;
Epidemiological characteristics;
Electronic medical record database
- From:
Chinese Journal of Epidemiology
2024;45(5):708-713
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To describe the incidence and epidemiological characteristics of immune thrombocytopenia (ITP) in Gansu Province from 2019 to 2022, and provide evidence for the diagnosis and treatment of ITP, related etiological research, and the association between ITP and vaccination.Methods:Descriptive epidemiological method was used to describe the characteristics of new confirmed ITP cases during 2019-2022 by using the data collected from the electronic medical record database of Gansu.Results:A total of 4 159 cases of ITP were newly diagnosed in Gansu from 2019 to 2022; with an overall incidence of 4.11/100 000 (95% CI: 3.98/100 000- 4.23/100 000), the incidence was 3.49/100 000 in men (95% CI: 3.33/100 000-3.65/100 000), and 4.74/100 000 in women (95% CI: 4.56/100 000-4.94/100 000), the difference was significant ( P<0.001). The incidence in children and the elderly was high, and the risk for ITP was higher in boys aged <10 years and men aged ≥80 years than in girls, and the risk was higher in adult women (20- 69 years) than in adult men. The incidence peak of ITP occurred in summer (June, July and August), and the incidence trough was in February or October in Gansu, and the annual incidence level in each age group showed cyclical changes. The risk for ITP was high in eastern and western areas, and low in central area. Conclusions:The incidence of ITP were high in children and the elderly in Gansu in 2019-2022, and men were at higher risk for ITP compared with women, and higher risk for ITP was observed in women in total population. There were also seasonal and regional specific high incidence.
