Association between unhealthy lifestyles and diabetic dyslipidemia in occupational population and network analysis
10.3760/cma.j.cn112338-20230715-00007
- VernacularTitle:职业人群不健康生活方式与糖脂代谢异常的关联及网络分析
- Author:
Chunlan MA
1
;
Bin YU
;
Yunzhe FAN
;
Tingting YE
;
Changwei CAI
;
Bo YANG
;
Honglian ZENG
;
Peng JIA
;
Shujuan YANG
Author Information
1. 四川大学华西公共卫生学院/华西第四医院,成都 610041
- Keywords:
Diabetic dyslipidemia;
Occupational population;
Network analysis;
Unhealthy lifestyle
- From:
Chinese Journal of Epidemiology
2024;45(3):425-431
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the influence of unhealthy lifestyle on diabetic dyslipidemia and the key influencing factors in occupational population and provided scientific evidence for the prevention of diabetic dyslipidemia.Methods:Based on baseline data and follow-up data of Southwest Occupational Population Cohort from China Railway Chengdu Group Co., Ltd. during 2021. Diabetic dyslipidemia was defined as diabetes plus one or more forms of dyslipidemia, and unhealthy lifestyle factors included smoking, alcohol consumption, unhealthy dietary patterns, low physical activity, and abnormal BMI. Multivariate logistic regression model was used to analyze the relationship between unhealthy lifestyle scores and diabetic dyslipidemia, network analysis was used to find and explore the key lifestyles influencing glycolipid metabolism.Results:A total of 25 631 subjects were included. People with unhealthy lifestyle score 2 and 3 were 1.93 (95% CI: 1.31-2.86) times and 2.37 (95% CI: 1.60-3.50) times more likely to have diabetes with ≥1 forms of dyslipidemia than those with scores of 0; People with unhealthy lifestyle score 1, 2 and 3 were 1.98 (95% CI: 1.08-3.61) times, 2.87 (95% CI: 1.60-5.14) times and 3.95 (95% CI: 2.22-7.06) times more likely to have diabetes with ≥2 forms of dyslipidemia than those with score 0. Network analysis found that abnormal BMI and HDL-C were the "bridge nodes" that link unhealthy lifestyles with diabetic dyslipidemia. Conclusion:The higher the score of unhealthy lifestyle, the higher the risk for diabetic dyslipidemia, abnormal BMI and HDL-C are key factors influencing the association between unhealthy lifestyle and diabetic dyslipidemia.