Disease burden of acute viral hepatitis in Guangdong Province, 1990-2019
10.3760/cma.j.cn112338-20230830-00108
- VernacularTitle:广东省1990-2019年急性病毒性肝炎疾病负担分析
- Author:
Jiamin QIU
1
;
Fangfang ZENG
;
Chen CHENG
;
Huiyan WEN
;
Shiqi HUANG
;
Dan LIU
;
Jinlei QI
;
Peng YIN
;
Maigeng ZHOU
;
Ying XU
;
Zhiping LIU
;
Qingsong MEI
;
Heng XIAO
;
Zheng XIANG
;
Xiaofeng LIANG
Author Information
1. 暨南大学基础医学与公共卫生学院预防医学系/暨南大学疾病预防与控制研究院/暨南大学康泰生物疫苗产业研究院，广州 510632
- Keywords:
Acute viral hepatitis;
Disease burden;
Trend analysis
- From:
Chinese Journal of Epidemiology
2024;45(3):365-372
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the burden and trends of acute viral hepatitis in Guangdong Province from 1990 to 2019, and provide reference evidences for hepatitis prevention and control in the province.Methods:Data on acute viral hepatitis (hepatitis A, B, C, and E) in Guangdong from 1990 to 2019 were extracted from the Global Burden of Disease Study 2019 database. The incidence, prevalence, mortality, and disability-adjusted life years (DALY) data were analyzed by age and gender, and the estimated annual percentage change (EAPC) was calculated to describe the changing trends in disease burden.Results:From 1999 to 2019, the standardized incidence, prevalence, mortality, and DALY of acute viral hepatitis in Guangdong were higher than the national averages. In 2019, 51.43% (2 245 087/4 365 221) of acute viral hepatitis cases in Guangdong Province were mainly attributed to hepatitis B, and 77.18% (106/138) of deaths were due to acute hepatitis B. In different age groups, except for acute hepatitis B, which was more common in adults, the incidence rates of other types of viral hepatitis such as hepatitis A, B, and E showed an overall decreasing trend with age. The mortality rates of different types of acute viral hepatitis, except for the <5 age group, increased with age. The overall incidence and mortality rates of acute viral hepatitis were higher in men than in women.Conclusions:The overall burden of acute viral hepatitis in Guangdong declined in 2019, but remained higher than the national level. Further efforts are needed to strengthen hepatitis prevention and screening in different population in Guangdong Province, especially in children and the elderly.
