Association between hair trace element and all-cause death in elderly people in Hainan
10.3760/cma.j.cn112338-20230420-00257
- VernacularTitle:海南高龄老人头发微量元素水平与全因死亡的关联分析
- Author:
Qiao ZHU
1
;
Jing LI
;
Shihui FU
;
Chaoxue NING
;
Yujian CHEN
;
Ting YANG
;
Hanwang ZHOU
;
Miao LIU
;
Yao HE
;
Yali ZHAO
Author Information
1. 解放军总医院海南医院中心实验室，三亚 572013
- Keywords:
Trace element;
All-cause death;
Elderly people
- From:
Chinese Journal of Epidemiology
2023;44(12):1936-1942
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the association between hair trace element and all-cause death in the elderly in Hainan Province.Methods:The subjects of the study were elderly people from China Hainan Centenarian Cohort Study, a total of 163 elderly were included. The association between hair trace element level and all-cause death was analyzed by using Cox proportional risk regression model.Results:After fully adjusting the covariates, the multiple Cox proportional hazards regression analyses showed that selenium (Se), manganese (Mn), strontium (Sr) concentrations in hair were significantly associated with all-cause mortality, the hazard ratio ( HR) were 0.72 (95% CI: 0.54-0.98, P=0.035), 1.50 (95% CI: 1.07-2.11, P=0.020) and 0.54 (95% CI: 0.37-0.79, P=0.001), respectively. Subgroup and cross analysis showed that hair copper (Cu) were significant association with death in the people with anemia, the HR were 1.81 (95% CI: 1.13-2.88, P=0.013). And, hair Mn interacted with anemia, the HR was 0.46 (95% CI: 0.22-0.94, P=0.033). Conclusions:Se, Mn and Sr concentrations in hair were associated with the elevated risk for all-cause death in the elderly in Hainan. Se, Mn and Sr concentrations in hair can be used as a reference index for the prediction of the death risk of long-lived elderly in community, suggesting that the daily diet of elderly people are rich and diverse, in order to maintain normal and balanced trace element content in the body.
