Study of influencing factors of seasonal influenza virus infection in pregnant women in Suzhou, 2015-2018
10.3760/cma.j.cn112338-20230322-00171
- VernacularTitle:苏州市2015-2018年孕产妇季节性流感病毒感染的影响因素研究
- Author:
Qian FENG
1
;
Yuanyuan ZHANG
;
Lin BAO
;
Yuanyuan PANG
;
Yayun TAN
;
Pengwei CUI
;
Jun ZHANG
;
Liling CHEN
Author Information
1. 南京医科大学公共卫生学院，南京 211166
- Keywords:
Influenza;
Pregnant woman;
Influencing factor
- From:
Chinese Journal of Epidemiology
2023;44(11):1748-1755
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influencing factors of seasonal influenza among pregnant woman in Suzhou from 2015 to 2018.Methods:Based on the data of the influenza follow-up cohort of pregnant women in Suzhou from 2015 to 2018, the basic and clinical characteristics of the cohort were described, and the influencing factors of laboratory-confirmed influenza cases in pregnant women were analyzed by unconditional logistic regression.Results:A total of 19 006 pregnant women were recruited, in whom 479 cases of influenza were laboratory confirmed. Influenza A (H3N2) (42.8%) was the main sub-type. In pregnant women with exposure risk in influenza season, unconditional univariate logistic analysis showed that pregnant women or their husbands had registered permanent residence in Suzhou, pregnant women worked as childminder or nanny, had more than 2 permanent residents in the family except themselves, had medical insurance in Suzhou, had fertility insurance in Suzhou, were in the third trimester at the time of enrollment, had cough in the past month, were pregnant for the first time, had children, before and after pregnancy, spent more time outdoors than before, wore masks more often than before and had changed the frequency of gathering were all related to influenza virus infection in pregnant women. Among them, the first pregnancy, increasing the time of outdoor activity, increasing the frequency of wearing masks, and changing the frequency of gathering were important protective factors. Unconditional multivariate logistic regression analysis showed that the number of permanent residents at home was >2 (a OR=1.24, 95% CI: 1.01-1.52) and being in the third trimester, (a OR=1.56, 95% CI: 1.26-1.91) were the risk factors for maternal infection with influenza virus. Conclusion:Pregnant women with a large number of permanent residents and late pregnancy should pay attention to preventing seasonal influenza.
