Analysis of parainfluenza virus infection in acute respiratory tract infection adult cases in Shanghai, 2015-2021
10.3760/cma.j.cn112338-20230404-00210
- VernacularTitle:上海市2015-2021年成年人急性呼吸道感染病例中副流感病毒感染情况分析
- Author:
Qi QIU
1
;
Huanyu WU
;
Huilin SHI
;
Hao PAN
;
Chenyan JIANG
;
Zheng TENG
;
Jiajing LIU
;
Yaxu ZHENG
;
Jian CHEN
Author Information
1. 上海市疾病预防控制中心传染病防治所，上海 200336
- Keywords:
Acute respiratory infection;
Parainfluenza virus;
Epidemic characteristics;
Mixed infection
- From:
Chinese Journal of Epidemiology
2023;44(10):1628-1633
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the infection status and epidemiological characteristics of parainfluenza virus (PIV) in acute respiratory tract infection adult cases in Shanghai from 2015 to 2021, and to provide a scientific basis for preventing and controlling PIV.Methods:Acute respiratory tract infections were collected from 13 hospitals in Shanghai from 2015 to 2021. Relevant information was registered, and respiratory specimens were sampled to detect respiratory pathogens by multiplex PCR.Results:A total of 5 104 adult acute respiratory tract infection cases were included; the overall positive rate of the respiratory pathogens was 29.37% (1 499/5 104). The positive rate of PIV was 2.61% (133/5 104), compared with 2.32% (55/2 369) and 2.85% (78/2 735) in influenza-like cases (ILI) and severe acute respiratory infection (SARI) cases, respectively. Among them, PIV3 accounted for the highest proportion (62.41%, 83/133), followed by PIV1 (18.80%, 25/133), PIV2 (9.77%, 13/133), and PIV4 (9.02%, 12/133). The incidence of PIV-positive cases was mainly distributed in the first and second quarters, accounting for 62.41% (83/133). The difference in the incidence in each quarter was significant ( χ2=24.78, P<0.001). Mixed infection accounted for 18.80% (25/133) of 133 PIV-positive cases, the mixed infection rates of ILI and SARI were 18.18% (10/55) and 19.23% (15/78), respectively, and the main mixed pathogen of PIV was coronavirus 229E. Conclusions:There are a certain proportion of PIV-positive acute respiratory tract infection cases in Shanghai. It is necessary to strengthen the etiological surveillance in acute respiratory tract infection cases, especially the mixed infection of PIV and other pathogens.
