Serum Calcium Level is Associated with Brachial-ankle Pulse Wave Velocity in Middle-aged and Elderly Chinese
- Author:
Ru Xin DENG
1
;
Fei Yin ZHANG
;
Ge Tian WANG
;
Hui Bai XU
;
Chao Ji SUN
;
Bin Lie ZHAO
;
Min XU
;
Hong Yu CHEN
;
Qing Wei WANG
;
Fang Yu BI
;
Li Jie LU
Author Information
- Keywords: Calcium; Brachial-ankle pulse wave velocity; Vascular stiffness
- From: Biomedical and Environmental Sciences 2014;(8):594-600
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relation between serum calcium level and elevated BaPWV in Chinese subjects.
Methods The relation between serum calcium level and elevated BaPWV was studied in 9 615 subjects. The mean value of left and right BaPWV was analyzed. BaPWV was defined as high when it was31 752.5 cm/s (the upper quartile) either side.
Results The BaPWV and its elevated percentage progressively increased across the quartiles of the serum calcium level (P<0.05). The prevalence of elevated BaPWV was significantly higher in subjects of the second, third and highest quartiles than in those of the lowest quartile (26.9%, 28.4%, and 33.2%vs 23.7%, P=0.0116, P=0.0004, and P<0.0001). Logistic regression analysis revealed that the risk of elevated BaPWV was 1.32- fold higher in subjects of the highest quartile than in those of the lowest quartile (OR=1.32, 95%CI:1.08-1.60).
Conclusion The elevated serum calcium level is related to an elevated BaPWV and a higher risk of arterial stiffness, independent of conventional risk factors, in middle-aged and elderly Chinese subjects.
