Association between 12 obesity related indicators and all-cause death in Hainan centenarians
10.3760/cma.j.cn112338-20220413-00290
- VernacularTitle:海南百岁老人12项肥胖相关指标与全因死亡的关联研究
- Author:
Shanshan YANG
1
;
Shengshu WANG
;
Rongrong LI
;
Shimin CHEN
;
Haowei LI
;
Xuehang LI
;
Yang SONG
;
Jianhua WANG
;
Yali ZHAO
;
Jing LI
;
Qiao ZHU
;
Chaoxue NING
;
Penggang TAI
;
Guangdong LIU
;
Miao LIU
;
Yao HE
Author Information
1. 解放军总医院第一医学中心疾病预防控制科，北京 100853
- Keywords:
Centenarian;
Anthropometric indicator;
All-cause death;
Cohort study
- From:
Chinese Journal of Epidemiology
2023;44(1):106-114
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To describe and analyze the relationship between traditional and new obesity related anthropometric indicators and all-cause death in centenarians in Hainan, the traditional and new obesity related anthropometric indicators included BMI, waist circumference (WC), waist hip ratio (WHR), waist height ratio, calf circumference (CC), waist-calf ratio (WCR), lipid accumulation product (LAP), visceral adiposity index (VAI), Chinese visceral adiposity index (CVAI), a body shape index (ABSI), a body shape index of Chinese (CABSI) and body roundness index.Methods:A total of 1 002 centenarians in Hainan were selected by cluster sampling. The M( Q1,Q3) follow-up time was 4.16 (1.31, 5.04) years and the outcome was all-cause death. Multiple Cox regression model was used to analyze the relationship between the obesity related anthropometric indicators and all-cause death, and the area under receiver operating characteristic curve was used for comparison. Results:In all the centenarians, CC had the strongest power to predict death, with area under curve (AUC) of 0.61 (95% CI:0.57-0.64), the gender specific results were consistent with that in overall population ( P<0.05), followed by WCR with AUC of 0.58, and then BMI, LAP and WC with AUC of 0.55, 0.55 and 0.54 respectively, while CABSI, WHR and VAI had the weaker power to predict death with AUC of 0.51, 0.50 and 0.50 respectively. Conclusions:This was the first study to prospectively compare and analyze the association between 12 obesity related anthropometric indicators and all-cause death in a large sample cohort of centenarians in China. It was found that CC had the best prediction power for death, and the risk for death decreased with the increase of CC value in a dose-response manner. It is suggested that CC can be used as a reference index for death risk monitoring in the elderly.
