Introduction of general population cohort study in southwestern China
10.3760/cma.j.cn112338-20221009-00864
- VernacularTitle:西南区域自然人群队列简介与研究进展
- Author:
Xing ZHAO
1
;
Feng HONG
;
Jianzhong YIN
;
Wenge TANG
;
Gang ZHANG
;
Xian LIANG
;
Jingzhong LI
;
Chaoying CUI
;
Xiaosong LI
Author Information
1. 四川大学华西公共卫生学院/四川大学华西第四医院，成都 610041
- Keywords:
China multi-ethnic cohort;
Southwestern China;
Research progress
- From:
Chinese Journal of Epidemiology
2023;44(1):40-47
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the burden of chronic and non-communicable diseases has become more serious in China, and the area specific heterogeneities are obvious. Southwestern China is a vast area with many ethnic groups and distinctive characteristics. While the local health resources are relatively limited, and the prevention and control of high-risk chronic diseases is challenging. In order to comprehensively analyze the disease distribution and potential exposure risk in populations in different ethnic groups in southwestern China, a natural population cohort study in southwestern China (multi-ethnic cohort study) was launched in 2017 with the support of the "Precision Medicine Research" Key Project, National Key Research and Development Program of China. At present, this cohort consists of 119 556 participants aged 30-79 years (18-79 years in Tibet Autonomous Region) and pregnant women in five provinces (municipality), i.e. Sichuan, Yunnan, Guizhou, Tibet, and Chongqing. A large-scale, multi-ethnic, high-quality natural population cohort with biobank has been established. The study has made some significant progress in the evaluation of the health impact of environmental and lifestyle factors in southwestern China and developed an innovative model for large cohort establishment in less developed areas. The results of this study can provide a reference for the establishment and research of large natural population cohorts in complex geographical scenarios, and serve as high-quality basic resources for China's precision medicine research and disease prevention and control decisions in areas with multi-ethnic groups.
