Design and performance of a prospective cohort study of common chronic and non-communicable diseases in central China
10.3760/cma.j.cn112338-20220921-00796
- VernacularTitle:华中区域常见慢性非传染性疾病前瞻性队列设计和建设概况
- Author:
Haiqing ZHANG
1
;
Chongjian WANG
;
Xiaotian LIU
;
Dan LUO
;
Shuiyuan XIAO
;
Handong YANG
;
Xiaomin ZHANG
;
Tangchun WU
Author Information
1. 华中科技大学同济医学院公共卫生学院劳动卫生与环境卫生学系，武汉 430030
- Keywords:
General population;
Cohort study;
Chronic and non-communicable disease;
Central China
- From:
Chinese Journal of Epidemiology
2023;44(1):34-39
- CountryChina
- Language:Chinese
-
Abstract:
With the advance of the economy and population aging, the acceleration of urbanization and the change of people's lifestyles, the prevalence of chronic diseases has become very serious. However, the etiologies and pathogeneses of the diseases are not yet clear, and the evidence of effective prevention and treatment strategies is lacking. Cohort study is an important method for exploring etiology and pathogenesis. Therefore, based on the support of the Ministry of Science and Technology for precision medicine in 2016, we launched a prospective cohort study of common chronic and non-communicable diseases in three provinces (Hubei, Hunan and Henan) in central China. Three independent and integratable sub-cohorts consisting of 115 424 participants at baseline survey and 107 252 participants in follow up were established, including dynamic measurements in 39 000 subjects in Dongfeng-Tongji prospective cohort. Each participant was asked to complete a questionnaire survey, an anthropometric measurement, a laboratory measurement, and blood and urine samples were collected from them. The cohort study contributes greatly to elucidating the etiologies and pathogeneses of common chronic and non-communicable disease in Chinese population and the development of precision medicine in China. This paper briefly introduces the design concept, basic information, major achievements and progress, and challenges of the prospective cohort study of common chronic and non-communicable diseases in central China.
