A review on the epidemiology of severe fever with thrombocytopenia syndrome
10.3760/cma.j.cn112338-20210529-00439
- VernacularTitle:发热伴血小板减少综合征流行病学研究进展
- Author:
Jiachen LI
1
;
Yuna WANG
;
Jing ZHAO
;
Hao LI
;
Wei LIU
Author Information
1. 病原微生物生物安全国家重点实验室，军事医学研究院微生物流行病研究所，北京 100071
- Keywords:
Severe fever with thrombocytopenia syndrome;
Epidemiological feature;
Risk factor
- From:
Chinese Journal of Epidemiology
2021;42(12):2226-2233
- CountryChina
- Language:Chinese
-
Abstract:
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease discovered in the 21 st century. This disease has been reported in several Asian countries, including China, Japan, South Korea, Vietnam, and Myanmar. Until 2019, SFTS cases have been reported in 25 provinces in China, and most of them were rural residents from mountains and hilly regions. Most SFTS cases were sporadic but geographically concentrated, mainly in Henan, Shandong, Anhui, Hubei, Liaoning, Zhejiang, and Jiangsu provinces. SFTSV infection was transmitted predominantly by a tick bite and potentially through close contact with the patient's blood or body fluids. Fever, gastrointestinal symptoms, thrombocytopenia, and leukopenia were common initial manifestations, and multiple organ failure or even death could occur in severe cases. The reported cases of SFTS have been gradually increasing, and the case fatality rate has remained at a high level, posing a severe threat to public health in China. This paper reviewed the epidemiological features, risk factors for disease transmission, and the clinical characteristics of SFTS to gain further knowledge of the disease, guide the prevention and management, and help reduce the case fatality rate.
