Progress in research of influential factors for non- or low-immune response to hepatitis B vaccination
10.3760/cma.j.cn112338-20200910-01145
- VernacularTitle:乙型肝炎疫苗免疫无/低应答影响因素的研究进展
- Author:
Juan LI
1
;
Mingwei WEI
;
Fengcai ZHU
Author Information
1. 南京医科大学公共卫生学院 211166
- Keywords:
Hepatitis B vaccine;
Non/low-response;
Influential factors
- From:
Chinese Journal of Epidemiology
2021;42(11):2066-2070
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus (HBV) can cause a variety of hepatitis B-related diseases in infected people, and there is no specific drug for treatment. China, with a large population base, is the country with the heaviest burden of HBV infection in the world. Therefore, hepatitis B vaccination is particularly important in the prevention and control of this disease. However, some vaccinees did not produce effective protective immune response after vaccination according to the recommended hepatitis B vaccine immunization schedule. The purpose of this review is to analyze the influential factors of non/low immune response after hepatitis B vaccination from the aspects of organism and vaccine, and explore the mechanism of non/low immune response, so as to provide scientific basis for the prevention and treatment of hepatitis B in China.
