Association between physical activity and risk of stroke among adults aged 40 years and above: a prospective cohort study
10.3760/cma.j.cn112338-20201010-01221
- VernacularTitle:基于人群的身体活动水平与脑卒中发病风险的队列研究
- Author:
Ge LOU
1
;
Sixuan LI
;
Qinghai GONG
;
Yinchao ZHU
;
Yanyan YING
;
Yong WANG
;
Yang LIU
;
Wenlan DONG
;
Shiwei LIU
;
Hui LI
Author Information
1. 中国疾病预防控制中心控烟办公室，北京 100050
- Keywords:
Stroke;
Risk factors;
Physical activity
- From:
Chinese Journal of Epidemiology
2021;42(6):1030-1036
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the effect of physical activity (PA) on the incident risk of stroke among adults aged 40 years and above.Methods:The baseline data including PA and demographic characteristics were obtained from the Adult Chronic Disease Surveillance with population representativeness in Ningbo in 2015. The follow-up data of interested health outcomes from 2015 to 2019 were retrieved from a population-based Integrated Noncommunicable Disease Collaborative Management System in Ningbo. The two databases were matched to form a queue. PA was divided into three levels of low-intensity, moderate-intensity, and vigorous-intensity according to the metabolic equivalents (METs) spent per week. Cox regression model was used to calculate the hazard ratio ( HR) and 95% confidence interval. Results:A total of 3 353 subjects were included at baseline survey in 2015. Until Dec 31, 2019, there had been 31 stroke events had occurred since then, with accumulative incidence rate of 242/100 000, and an average follow-up time of (50.28±2.54) months. When adjusted for gender, age, education level, smoking status, alcohol consumption, BMI and hypertension, multivariate Cox regression analysis showed that greater PA was associated with a 37.9% reduction of incidence of stroke ( HR=0.621,95% CI:0.393-0.983). Compared with those who had low-intensity PA, those who were with vigorous-intensity. PA appeared associated with a 63.1% decrease in the incidence of stroke ( HR=0.369, 95% CI: 0.139-0.976). However, there was no statistical significance with moderate-intensity PA ( HR=0.712,95% CI:0.323-1.569), noticed. Conclusions:Greater PA is likely to reduce the incidence of stroke. Our findings indicated that people should be encouraged to increase the PA level and developing a healthy supportive environment in the community.
