Profile of China National Birth Cohort
10.3760/cma.j.cn112338-20201211-01402
- VernacularTitle:中国国家出生队列建设背景和设计简介
- Author:
Zhibin HU
1
;
Jiangbo DU
;
Xin XU
;
Yuan LIN
;
Hongxia MA
;
Guangfu JIN
;
Rong LI
;
Junhao YAN
;
Zhiwei LIU
;
Ge LIN
;
Canquan ZHOU
;
Yankai XIA
;
Hongbing SHEN
Author Information
1. 南京医科大学公共卫生学院流行病学系 211166
- Keywords:
Birth cohort;
China National Birth Cohort;
Assisted reproductive technology;
Spontaneous pregnancy
- From:
Chinese Journal of Epidemiology
2021;42(4):569-574
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid changes in lifestyle, natural and social environment, the reproductive health status of couples in childbearing age continues to decline, and long-term outcomes of the rapidly increasing offspring conceived by assisted reproductive technology (ART) needs to be evaluated urgently. Therefore, the focus of research now needs to be extended from death and severe diseases to full life cycle and full disease spectrum. In order to meet the demand for such research, we launched the China National Birth Cohort (CNBC) study, an ongoing prospective and longitudinal study aiming to recruit 30 000 families underwent ART and 30 000 families with spontaneous pregnancies. Long-term follow-up programs will be conducted for both spouses and their offspring. Data of couples and their offspring, such as environmental exposure, reproductive history, psychological and behavioral status, will be collected during follow-up. Peripheral blood, urine, umbilical blood, follicular fluid, semen were also collected at different follow-up nodes. Based on high-quality data and biological samples, CNBC will play an extremely important supporting role and have a far-reaching impact on maternal and children's health care and reproductive health in China. This paper is exactly a brief introduction to the construction and basic design of CNBC.
