Change in obesity status and development of cardiometabolic disorders in school-age children
10.3760/cma.j.cn112338-20200812-01060
- VernacularTitle:学龄儿童肥胖持续状态与心血管代谢异常发病风险
- Author:
Dongqing HOU
1
;
Hongbo DONG
;
Zhongxin ZHU
;
Zhaocang YU
;
Hongjian WANG
;
Aiyu GAO
;
Hong CHENG
;
Xiaoyuan ZHAO
;
Junting LIU
;
Guimin HUANG
;
Fangfang CHEN
;
Jie MI
Author Information
1. 首都儿科研究所流行病学研究室，北京 100020
- Keywords:
Children;
Obesity;
Cardiometabolic disorder;
Cohort study
- From:
Chinese Journal of Epidemiology
2021;42(3):440-447
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the influence of obesity status on the development of cardiometabolic disorders in school-age children.Methods:Information about children's body weight, body height and cardiovascular risk factors were collected in baseline survey in 2017 and follow-up survey in 2019. The school-age children were divided into four groups based on their baseline and follow-up obesity status, i.e. sustained non-obesity group, restored obesity group, newly classified obesity group, and persistent obesity group. Analysis of covariance was used to compare the difference of change in levels of cardiometabolic factors among the four groups. The multivariate logistic regression model was used to analyze the relationship between obesity status and the incidence risk of cardiometabolic disorders.Results:The present study included 11 379 school-age children (boys accounting for 49.6%). During the 2 years, the incidence of obesity was 3.2% (95% CI: 2.9%-3.5%) with the restoration ratio of obesity of 4.4% (95% CI: 4.0%-4.8%). Compared with the sustained non-obesity group, increases in SBP, DBP, TG, LDL-C and non-HDL-C were much higher in newly classified obesity group and persistent obesity group, but lower in restored obesity groups except for DBP (all P<0.05). In addition, the incidence risk of hypertension, high glucose, dyslipidemia and cardiometabolic disorders (≥2 risks) were much higher in newly classified and persistent obese children than in sustained non-obese children. No difference was found in incidence risks of most cardiovascular disorders between restored obese children and sustained non-obese children, except for hypertension and cardiometabolic risks. Conclusion:Both newly classified obesity and persistent obesity increased the incidence risks for multi cardiovascular disorders, while these risks could be reduced when non-obese status restore.
