Prevalence of HBV co-infection in HIV-positive population in China: a systematic review and Meta-analysis
10.3760/cma.j.cn112338-20200727-00987
- VernacularTitle:我国HIV感染者合并感染HBV现况
- Author:
Yang CAO
1
;
Minghao ZHOU
;
Xiangjun ZHAI
Author Information
1. 南京医科大学公共卫生学院 211166
- Keywords:
HIV positive population;
HBV prevalence;
Meta-analysis
- From:
Chinese Journal of Epidemiology
2021;42(2):327-334
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To reveal the epidemiologic characteristics of hepatitis B virus (HBV) infection in HIV positive population in China.Methods:We collected research papers published from 2010 to 2019 on HBV co-infection in HIV positive population in China through literature retrieval, screening and quality evaluation. The Meta-analysis was conducted after extracting relevant data from the research papers meeting the inclusion criteria.Results:Twenty-seven studies were included with 69 816 samples. The pooled HBV infection rate in HIV positive population in China was 11.29%. The HBV co-infection rate was higher in the western China (10.73%) and southern China (14.18%), while lower in northern China (6.36%). The HBV infection rates were 11.22%, 12.76%, 9.58%, 11.32% and 10.34%, respectively, in HIV-positive population infected through blood or blood products transfusion, intravenous drug use, homosexual contact, heterosexual contact and unknown transmission routes. Population infected with HIV caused by mother-to-child transmission had the lowest HBV infection rate (2.87%). The HBV infection rate in HIV positive males was 1.29 times higher than that in HIV positive females in southern China.Conclusions:The HBV infection rate in HIV positive population is significantly higher than that in general population. More attention should be paid to the prevention and control of HBV co-infection in HIV positive population.
