Association between serum albumin level and health-related quality of life in Hainan centenarians: a cross-sectional study
10.3760/cma.j.cn112338-20200424-00637
- VernacularTitle:海南百岁老人血清白蛋白水平与健康相关生活质量的关联性研究
- Author:
Ke HAN
1
;
Shengshu WANG
;
Wangping JIA
;
Shanshan YANG
;
Wenzhe CAO
;
Yali ZHAO
;
Qiao ZHU
;
Chaoxue NING
;
Miao LIU
;
Yao HE
Author Information
1. 解放军总医院老年医学研究所，衰老与相关疾病研究北京市重点实验室，肾脏疾病国家重点实验室，国家老年疾病临床医学研究中心，北京 100853
- Keywords:
Serum albumin;
Centenarian;
Hainan;
Health-related quality of life;
Cross-sectional study
- From:
Chinese Journal of Epidemiology
2021;42(1):88-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the association between serum albumin levels and health-related quality of life in centenarians in Hainan province, China.Methods:We conducted a full sample centenarian cohort study in a community population in Hainan from 2014 to 2016, which included 1 002 centenarians for questionnaire surveys, physical examinations and biological tests. The EQ-5D-VAS scale was used to evaluate health-related quality of life, and multiple linear regression and multiple logistic regression analyses were used to analyze the association between serum albumin levels and health-related quality of life.Results:There was a positive linear relationship between serum albumin levels and EQ-5D/VAS score. The normalized β values in the fully adjusted model was 0.156 ( P<0.001). In the multivariate logistic regression analysis, after fully adjusting the covariates, the risk of health related life quality impairment in the lower albumin group was 2.369 times(95% CI: 1.424-3.939) than that in the higher albumin group. Gender stratified analyses showed that the OR was 4.406 (95% CI: 1.537-12.631) in male centenarians and 2.035 (95% CI: 1.125-3.680) in female centenarians. Conclusion:Lower serum albumin level was associated with impaired health-related quality of life in centenarians in Hainan.
