Relationship between sedentary time and incidence of type 2 diabetes in adults in China: a prospective cohort study
10.3760/cma.j.cn112338-20190926-00705
- VernacularTitle:中国成年人静坐时间与2型糖尿病发病关系的前瞻性队列研究
- Author:
Xiangfeng CONG
1
;
Shaobo LIU
;
Tingling XU
;
Wenjuan WANG
;
Jixiang MA
;
Bo CHEN
;
Jianhong LI
Author Information
1. 中国疾病预防控制中心慢性非传染性疾病预防控制中心，北京 100050
- Keywords:
Sedentary time;
Type 2 diabetes;
Prospective study
- From:
Chinese Journal of Epidemiology
2020;41(9):1465-1470
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between sedentary time and the incidence of type 2 diabetes in adults in China.Methods:Data collected from the Chinese Chronic Disease and Risk Factor Surveillance (CCDRFS) in 2010 were used as baseline data. Eight provinces where CCDRFS were conducted in 2010 were selected, and two surveillance spots (one in urban area and another one in rural area) of each provinces were further selected for the follow-up studies. After excluding diagnosed diabetes patients according to baseline data, a total of 8 625 of subjects were recruited as participants. In the follow up carried out from 2016 to 2017, a total of 5 991 people received complete follow up. Cox proportional hazards models were used to analyze the relationship between sedentary time and the incidence of type 2 diabetes, and subgroup analysis was conducted based on variables such as gender, geographic area, and urban area or rural areas.Results:A total of 5 782 subjects were included in final analysis. During an average 6.4 years of follow up (36 927.0 person-years), 592 participants developed type 2 diabetes, the incidence rate was 16.0 per 1 000 person years. Multivariate Cox regression analysis showed that after adjustment for possible confounders, compared with the 0.0-h/d group, the risk of diabetes incidence increased by 33% ( HR=1.33, 95 %CI: 1.05-1.68) for those who had sedentary time for more than 6.0 h every day. The subgroup analysis showed that the significant association was only observed in those who were men, current smokers, central obese, had family history of diabetes, had rural residency, and lived in eastern and central areas of China. Conclusions:Longer sedentary time can increase the risk of type 2 diabetes. Lifestyle intervention should be strengthened to reduce sedentary time, especially for people who had sedentary time for more than 6.0 h every day.
