Characteristics on molecular epidemiology of Brucella melitensis in Jiangxi province
10.3760/cma.j.cn112338-20191225-00916
- VernacularTitle:江西省羊种布鲁氏菌分子流行病学特征分析
- Author:
Jun ZONG
1
;
Sheng DING
;
Guozhong TIAN
;
Guanghui XIA
;
Changhui XIONG
;
Peng WANG
;
Xiaoqian XU
;
Jianmin XU
Author Information
1. 江西省疾病预防控制中心，南昌 330029
- Keywords:
Brucella melitensis;
Multiple locus variable-number tandem repeat analysis;
Simpson index;
Type
- From:
Chinese Journal of Epidemiology
2020;41(8):1341-1344
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the molecular characteristics and correlation among isolated strains of Brucella melitensis (BM) so as to improve the strategies on prevention and control of the disease in Jiangxi province. Methods:A total of 25 strains of BM isolated from human in 17 counties of Jiangxi province were analyzed by multiple locus variable-number tandem repeat analysis (MLVA) method.Results:A total of 25 strains of BM were classified into 24 independent genotypes with similarities between 67.00% and 100.00% and Simpson index between 0.000 and 0.773. There were 3 genotypes in MLVA8, including 60.00% (15/25) as 42 genotype, 32.00% (8/25) as 43 genotype, and 8.00% (2/25) as 63 genotype, respectively. There were 7 genotypes in MLVA11 identified, with 116 genotype and 125 genotype the main genotypes, accounting for 56.00% (14/25) of all the identified strains.Conclusions:Genes from all the 25 strains of BM that isolated from human being were with high genetic diversities, and various, genotypes. However, no obvious epidemiological correlation was noticed among these strains, indicating the complexity of the source of infection on Brucella in Jiangxi province.
