Association between tooth missing and non-alcoholic fatty liver disease
10.3760/cma.j.cn112338-20190621-00457
- VernacularTitle:缺失牙数与非酒精性脂肪肝的相关研究
- Author:
Kaiyu FU
1
;
Feng QIAO
;
Ge MENG
;
Qing ZHANG
;
Li LIU
;
Kun SONG
;
Kaijun NIU
Author Information
1. 天津医科大学研究生院 300070
- Keywords:
Non-alcoholic fatty liver disease;
Tooth missing;
Periodontal disease
- From:
Chinese Journal of Epidemiology
2020;41(5):716-721
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the association between the number of teeth missed and the prevalence of non-alcoholic fatty liver disease (NAFLD) in adults.Methods:A cross-sectional study was carried out in 26 983 adults from Tianjin Chronic Low-grade Systemic Inflammation and Health Cohort Study. The number of teeth missed (excluding third molars) was recorded and classified into four categories: 0, 1-, 3- and ≥6. NAFLD was diagnosed by at least two liver ultrasonography examinations. Adjusted multivariable logistic regression analysis was used to access the association between the number of missed teeth and NAFLD in adults.Results:The overall prevalence of NAFLD was 7 270 and the number of the subjects with at least one tooth missed was 9 667. The multivariable-adjusted ORs (95% CI) of NAFLD across the categories of tooth missing (0, 1-, 3- and ≥6) were as follows: 1.00, 1.04 (0.93-1.15), 1.08 (0.93-1.26) and 1.38 (1.09-1.76) (trend test P=0.030) in males; 1.00, 0.96 (0.82-1.12), 1.11 (0.91-1.35) and 1.22 (0.90-1.64) (trend test P=0.450) in females. Conclusion:The number of missed teeth was positively associated with a higher prevalence rate of NAFLD in males with over 6 teeth missed, but not in females.