Trend analysis on the disease burden related to cirrhosis and other chronic liver diseases caused by hepatitis B, in China, from 1990 to 2016
10.3760/cma.j.issn.0254-6450.2020.02.007
- VernacularTitle:1990-2016年中国乙型肝炎引起的肝硬化及其他慢性肝病疾病负担变化趋势分析
- Author:
Lu ZHANG
1
;
Zhifang FAN
;
Dianwu LIU
;
Maigeng ZHOU
;
Zhuoqun WANG
;
Man LI
Author Information
1. 河北医科大学公共卫生学院流行病与卫生统计学教研室河北省环境与人群健康重点实验室
- Keywords:
Hepatitis B;
Cirrhosis;
Burden of disease;
Disability adjusted life year
- From:
Chinese Journal of Epidemiology
2020;41(2):173-177
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of this study was to analyze the disease burden of cirrhosis and other chronic liver diseases caused by hepatitis B in China,from 1990 to 2016,and to provide evidence for the development of related strategies.Methods Data were collected from the results of the Global Burden of Disease Study 2016 (GBD2016).We analyzed the current epidemiological patterns by calculating the prevalence,mortality,and disability adjusted life year (DALY) of cirrhosis and other chronic liver diseases,caused by hepatitis B during 1990 and 2016 in China.Results Compared with data from 1990,the number of patients and deaths with cirrhosis and other chronic liver diseases caused by hepatitis B in 2016 increased by 79.6％ and 2.4％,respectively.The prevalence increased by 49.2％,higher (50.3％) in males than that (42.3％) in females.Compared with other age groups,the increase (33.2％) of prevalence appeared the fastest,in the 15-49 age group.In males,the number of deaths and DALYs increased by 13.6％ and 2.2％,respectively.In 2016,the five top provinces on age-standardized DALY rates,appeared as Qinghai (314.6 per 100 000),Guizhou (303.1 per 100 000),Yunnan (262.4 per 100 000),Guangxi Zhuang Autonomous Region (239.6 per 100 000) and Taiwan (227.2 per 100 000).Conclusions From 1990 to 2016,the prevalence rates of hepatitis B related cirrhosis and other chronic liver diseases showed an upward trend,particularly in males and in people aged 15 to 49 years old,in China.However,the disease burden of different provinces was unevenly distributed.Based on our findings,we suggested that strategies that related to prevention and management of hepatitis B caused cirrhosis and other chronic liver diseases should be paid more attention to.
