Enamel developmental defects: environmental factors and clinical management
10.3760/cma.j.cn112144-20230905-00140
- VernacularTitle:牙釉质发育缺陷性疾病的环境影响因素及临床管理
- Author:
Yiting LI
1
;
Qinglu TIAN
;
Pengcheng HE
;
Liwei ZHENG
Author Information
1. 四川大学华西口腔医院儿童口腔科 口腔疾病防治全国重点实验室 国家口腔医学中心 国家口腔疾病临床医学研究中心, 成都 610041
- Keywords:
Dental enamel;
Development of enamel;
Developmental defects of enamel;
Environmental factors;
Early life;
Clinical management strategy
- From:
Chinese Journal of Stomatology
2023;58(11):1197-1203
- CountryChina
- Language:Chinese
-
Abstract:
Enamel formation is a complex physiological process that depends on the coordinated regulation of multiple mechanisms. This process is quite sensitive to various local and systemic interference factors. Therefore, during the long period from the embryonic stage to adolescence or even adulthood, various interference factors may lead to enamel developmental defects. Among them, early life is the most sensitive stage to environmental factors exposure, while it is also the critical period of enamel development of deciduous and permanent teeth. Environmental factors exposure during this period often leads to varying degrees of enamel development defects. In this review, we generalize the research progress of environmental factors affecting enamel developmental defects, summarize the potential mechanisms of environmental factors leading to enamel developmental defects, and conclude the clinical management strategies based on tertiary prevention. This work hopes to provide a theoretical basis for preventing abnormal teeth development from the critical time window of early life, propose eugenics health consultation and promote children ′s oral health management.
