Oral microbiome dysbiosis triggers gestational periodontal disease and adverse pregnancy outcomes
10.3760/cma.j.cn112144-20220410-00166
- VernacularTitle:口腔微生态失衡与妊娠期牙周病和不良妊娠结局的相关性研究进展
- Author:
Changchang YE
1
;
Yafei WU
Author Information
1. 四川大学华西口腔医院牙周病科 口腔疾病研究国家重点实验室 国家口腔疾病临床研究中心，成都610041
- Keywords:
Periodontics;
Periodontitis;
Oral microbiome dysbiosis;
Gestational periodontal diseases;
Periodontal pathogens;
Adverse pregnancy outcomes
- From:
Chinese Journal of Stomatology
2022;57(6):635-641
- CountryChina
- Language:Chinese
-
Abstract:
Oral microbiome dysbiosis, triggered by increased oral pathogens or decreased commercial bacteria, leads to oral and systemic diseases. Recent ecological events suggest that periodontal disease is a risk factor of adverse pregnancy outcomes. The oral microbiome dysbiosis is believed to be associated with oral disease and adverse pregnancy outcomes (APO). However, the pathogenic mechanisms have not yet been elucidated. In this review, we summarize the recent literature on how pregnancy associated pathogenic oral microbiome dysbiosis can trigger gestational periodontal diseases and poor birth outcomes, especially the role of periodontal pathogenic bacteria in the mechanisms of how gestational periodontal diseases cause APO, and the effect of periodontal therapy during pregnancy on birth outcomes.
