Research progress in Filifactor alocis interacting with periodontitis
10.3760/cma.j.cn112144-20210113-00015
- VernacularTitle:龈沟产线菌与牙周炎关系的研究进展
- Author:
Fangting HUANG
1
;
Biao REN
;
Jiyao LI
Author Information
1. 四川大学华西口腔医院牙体牙髓科 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心，成都 610041
- Keywords:
Periodontitis;
Filifactor alocis;
Periodontal pathogens;
Microbial interactions;
Immune response
- From:
Chinese Journal of Stomatology
2021;56(10):1034-1039
- CountryChina
- Language:Chinese
-
Abstract:
Many new microbial species which are correlated with periodontitis have been identified in addition to the"red complex"cultured by conventional methods due to the development of high-throughput sequencing technology. Filifactor alocis (Fa), as a anaerobic Gram-positive bacteria, is closely related to the occurrence and development of periodontitis. Fa can not only destroy host cells and induce immune escape response, but also interact with other periodontal pathogens to promote the periodontitis. This article summarizes and discusses the research progress on the relationship between Fa and periodontitis in recent years and highlighs a new way to investigate the etiology, prevention and treatment of periodontitis.
