Effect of trace elements on the differentiation of dental pulp stem cells

VernacularTitle:微量元素对牙髓干细胞分化的影响
Author: Zitian LIANG ¹ ; Tingting LIANG ; Qianzhou JIANG ; Li YANG
Author Information

1. 广州医科大学附属口腔医院牙体牙髓科·广州口腔疾病研究所·口腔医学重点实验室　510140
Keywords: Trace elements; Stem cells; Mesenchymal stem cells; Cell differentiation; Dental pulp stem cells
From: Chinese Journal of Stomatology 2021;56(6):604-607
CountryChina
Language:Chinese
Abstract: Dental pulp stem cell (DPSC), with a high capacity of multidirectional differentiation, is the key and preferred cell in the study of dental pulp and dentin regeneration. The effect of trace elements on the differentiation of DPSC is one of the research hotspots in the field of oral tissue engineering in recent years. Trace elements have a wide range of physiological and biochemical functions. It can directly regulate the differentiation, migration and proliferation capacity of DPSC, while can indirectly affect the differentiation of DPSC by exerting antibacterial and immune function regulation or changing the physical and chemical properties of the scaffold material. To clarify the role of trace elements in the differentiation of DPSC can provide more reference for the realization of pulp and dentin regeneration. This paper will review the recent research progress on the effects of relevant trace elements on the differentiation of DPSC into odontogenesis and angiogenesis.