Research advances in the interaction of periodontitis and psoriasis
10.3760/cma.j.cn112144-20210128-00043
- VernacularTitle:牙周炎与银屑病相关关系的研究进展
- Author:
Ye LIANG
1
;
Jinlong SHAO
;
Shaohua GE
Author Information
1. 山东大学齐鲁医学院口腔医学院·口腔医院牙周科 山东省口腔组织再生重点实验室 山东省口腔生物材料与组织再生工程实验室，济南 250012
- Keywords:
Periodontitis;
Psoriasis;
Inflammation mediators;
Risk factors
- From:
Chinese Journal of Stomatology
2021;56(6):591-597
- CountryChina
- Language:Chinese
-
Abstract:
Periodontitis is a common chronic infectious oral disease, which is characterized by gingival inflammation,pocket formation, alveolar bone loss and tooth mobility. Psoriasis is a common chronic inflammatory skin disease, whose pathological features in skin lesions are excessive proliferation of epidermal cells, parakeratosis of the derma, and the infiltration of inflammatory cells. Both periodontitis and psoriasis are closely related to the interleukin(IL)-23/helper T cell 17(Th17)/IL-17 axis in their immunopathological mechanisms. The risk factors of psoriasis include smoking, vitamin D deficiency, obesity, emotional stress, etc, of which most factors are also common risk factors of periodontitis. The present article reviews the research advances in the interaction of the two diseases and their possible common mechanisms from three aspects, i.e. clinical study, IL-23/Th17/IL-17 pathway and common risk factors, which may be helpful to provide new ideas for clinical diagnosis and treatment.
