Roles of periodontal pathogens in the pathogenesis of atherosclerosis
10.3760/cma.j.cn112144-20210222-00085
- VernacularTitle:牙周致病菌在动脉粥样硬化发生发展中的作用研究
- Author:
Daonan SHEN
1
;
Yafei WU
;
Lei ZHAO
Author Information
1. 四川大学华西口腔医院牙周病科 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心, 成都 610041
- Keywords:
Periodontitis;
Cardiovascular disease;
Periodontal pathogens;
Atherosclerosis
- From:
Chinese Journal of Stomatology
2021;56(6):584-590
- CountryChina
- Language:Chinese
-
Abstract:
Periodontitis is closely related to systemic health, especially cardiovascular disease. Periodontal pathogens from periodontal infection actively participate in the formation and development of coronary atherosclerosis. At present, accumulcted evidences show that periodontal pathogen infection is an independent risk factor for cardiovascular events, which promotes the deepening of atherosclerosis through a variety of immune inflammation and metabolism-related molecular mechanisms. The present article reviews multipal aspects of the correlation between periodontitis and periodontal pathogens and cardiovascular disease, and the mechanism of periodontal pathogens affecting the occurrence and development of atherosclerosis.
