Research progress of liposome drug delivery system in stomatology
10.3760/cma.j.cn112144-20200627-00372
- VernacularTitle:脂质体药物递送系统在口腔医学中的研究进展
- Author:
Zhimin HU
1
;
Siying LIU
;
Hongye YANG
;
Cui HUANG
Author Information
1. 武汉大学口腔医学院口腔基础医学省部共建国家重点实验室培育基地和口腔生物医学教育部重点实验室 430079
- Keywords:
Liposome;
Oral Medicine;
Drug delivery system
- From:
Chinese Journal of Stomatology
2021;56(3):294-300
- CountryChina
- Language:Chinese
-
Abstract:
Liposomes are spherical vesicles with bilayer membrane structure spontaneously formed by phospholipids dispersed in an aqueous medium. Liposomes are excellent drug carrier with amphiphilic properties. Liposomes have good biocompatibility, biodegradability and no immunogenicity. Liposomes can achieve the delivery of the drug, enhance the solubility, improve the stability, reduce the toxic effect of the drug, and improve the therapeutic effect of the loaded drug. In recent years, liposome drug delivery systems have been widely used in dentistry. This article reviews the application of liposome drug delivery systems in caries, dental pulp diseases, periodontitis, implantation, oral anesthesia and oral candidiasis.
