Research progress in standardized dental treatments of patients receiving bisphosphonate

VernacularTitle:对使用双膦酸盐患者进行规范化口腔治疗的研究进展
Author: Xuan BAI ¹ ; He YUAN ; Jiyao LI
Author Information

1. 四川大学华西口腔医院牙体牙髓科　口腔疾病研究国家重点实验室　国家口腔疾病临床医学研究中心，成都　610041
Keywords: Biphosphonates; Osteonecrosis; Invasivedental treatment; Standardized treatment
From: Chinese Journal of Stomatology 2020;55(10):783-788
CountryChina
Language:Chinese
Abstract: Bisphosphonate (BP), a group of anti-resorptive drugs, has been widely used for the treatments of osteoporosis and metastatic bone diseases. Medication-related osteonecrosis of the jaw (MRONJ), a serious well-recognized complication of patients receiving BP, adversely affects patients′ oral health and quality of life. Its clinical signs include pain, bone exposure and necrosis of the jaws. Invasive oral treatments, which may affect the repair of jaws in patients using BP, could cause the occurrence of MRONJ. Therefore, it is important to avoid the risk factors of MRONJ and to standardize the operations in order to reduce the occurrence of MRONJ in oral treatments for patients receiving BP. After reviewing the related literature, this article aims to conclude the research progress on the standardized oral treatments of patients receiving BP and to provide clinical instructions for clinicians to treat these patients.