Clinical Significance of Platelet Index in Posttreatment Follow-up of Vivax Malaria.
- Author:
Chae Seung LIM
1
;
Young Kee KIM
;
Kap No LEE
Author Information
1. Department of Clinical Pathology, College of Medicine, Korea University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Vivax malaria;
Treatment;
Blood count;
Platelet
- MeSH:
Blood Cell Count;
Blood Platelets*;
Follow-Up Studies*;
Humans;
Korea;
Malaria;
Malaria, Vivax*;
Parasitemia;
Platelet Count
- From:Korean Journal of Infectious Diseases
1998;30(5):439-442
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: In Korea, vivax malaria has progressively increased to 1,700 cases in 1997. To prevent the spread of malaria, early detection and treatments, as well as vector control programs, are essential. Until now, classic methods, such as thin and thick blood smears with Giemsa or Wright stain have been routinely used as follow-up after anti-malarial treatment, but these require expertise. We evaluated here hematologic indices as makers in follow-up after anti-malarial treatment. METHODS: Thin and thick blood smears were prepared in 22 patients at pre- and posttreatment periods. The slides were stained with Giemsa or Wright Giemsa solution. Simultaneously complete blood cell counts including 10 hematologic indices (WBC, RBC, Hb, Hct, MCV, MCH, MCHC, RDW, Platelet, MPV) were done by autoanalyser Celldyn 3000. We analysed correlation between parasitemia and each hematologic index and significant changes between pre- and posttreatment. RESULTS: Other indices were not significantly changed after anti-malarial treatment, except for platelet counts which inversely correlated with parasitemia. Mean platelet counts of patients were recovered from 97,000/uL to 14,1000/uL in posttreatment follow-up. CONCLUSION: Platelet counts in malaria patients could be used as simple and useful marker for posttreatment follow-up.
