Gene mutations and disorders of dental hard tissues
10.3760/cma.j.cn112144-20200225-00086
- VernacularTitle:基因突变与牙体硬组织发育异常
- Author:
Yaling SONG
1
;
Zhuan BIAN
Author Information
1. 武汉大学口腔医学院特诊科 430079
- Keywords:
Dental enamel hypoplasia;
Dentinogenesis imperfecta;
Dentin dysplasia;
Gene mutation
- From:
Chinese Journal of Stomatology
2020;55(5):316-322
- CountryChina
- Language:Chinese
-
Abstract:
Developmental disorders of dental hard tissues are important components of non-carious diseases, which mainly include amelogenesis imperfecta and hereditary dentin disorders with various subtypes. In the absence of effective intervention, these disorders would lead to tooth sensitivity, defects of tooth structure or even loss of tooth, affecting the masticatory function and facial aesthetic configuration. At present, many dental clinicians may not have sufficient understanding of the diseases, and it is urgent to pay attention to the diseases per se and the patients affected. Based on the summary of the current research progresses, this article focuses on the clinical classification, the disease phenotype and the pathogenesis of gene mutations, in order to provide reference and help for the dental clinicians as well as the patients.
