Protein-repellent and antibacterial properties of modified orthodontic adhesive

VernacularTitle:甲基丙烯酰氧乙基磷酸胆碱对正畸粘接剂抗蛋白附着和抗菌性的影响
Author: Ning ZHANG ¹ ; Yansong MA ; Huakun XU ; Yuxing BAI
Author Information

1. 100050,首都医科大学口腔医学院正畸科
Keywords: Bacterial adhesion; Shear strength; Resin cements; 2-methacryloyloxyethyl phosphorylcholine
From: Chinese Journal of Stomatology 2016;51(9):558-561
CountryChina
Language:Chinese
Abstract: Objective To develop a novel protein-repellent orthodontic adhesive by incorporating 2-methacryloyloxyethyl phosphorylcholine(MPC).Methods MPC was incorporated into a commercially available orthodontic adhesive(Fuji ORTHO) at 0％ (control),1.5％,3.0％,and 5.0％ by mass.Enamel shear bond strength(SBS) was determined.Protein adsorption onto specimens was determined by a micro bicinchoninic acid method.A dental plaque microcosm biofilm model with human saliva as inoculum was used to investigate biofilm viability.Results The SBS was not reduced in the group(3.0％ MPC),compared to the control group.The amount of protein adsorption in the group(3.0％ MPC) was (0.46±0.06) μg/cm2 and (4.57 ± 0.42) μg/cm2 in the control group.Lactic acid production of biofilms in the group(3.0％ MPC) was (7.12± 1.03) mmol/L and (12.16± 1.24) mmol/L in the control group.Conclusions MPC based orthodontic adhesive greatly reduced the protein adsorption and bacterial adhesion,without compromising enamel shear bond strength.