The progress in application of parathyroid hormone in craniomaxillofacial bone regeneration study
10.3760/cma.j.issn.1002-0098.2016.06.012
- VernacularTitle:甲状旁腺激素在颅颌面骨再生研究中的应用进展
- Author:
Xiaoyan CHEN
1
;
Zhenglong TANG
Author Information
1. 贵州医科大学附属医院口腔颌面外科
- Keywords:
Parathyroid hormone;
Bone regeneration;
Bone Remodeling
- From:
Chinese Journal of Stomatology
2016;51(6):379-382
- CountryChina
- Language:Chinese
-
Abstract:
Parathyroid hormone(PTH) is synthesized and secreted by chief cell of Gley's glands which possesses dual functions of catabolism and anabolism.It regulates the proliferation and differentiation of multiple cell lines including osteoblast,osteoclast and skeletal lining cells.Furthermore,PTH activates various signaling pathways which control calcium,phosphorous' metabolism and bone conversion,accelerating the bone regeneration and reconstruction.However,the study of PTH in craniomaxillofacial bone regeneration is relatively less and whether the role of parathyroid glands and the mechanism of ossification are consistent with the long bone or not needs further investigation.This review focuses on the progress of PTH in craniomaxillofacial bone regeneration in recent years.
