Assessment of the urine and serum levels of nickel and chromium in patients before and after removal the nickel-chromium alloy porcelain-fused-to-metal restoration
10.3760/cma.j.issn.1002-0098.2012.s1.036
- VernacularTitle:镍铬合金烤瓷修复体拆除前后患者尿和血清中镍铬含量的评估
- Author:
Da-Wei GUO
1
;
Fang YANG
;
Xiao YUAN
;
Zheng-Gang CHEN
;
Jing-Wen LI
;
Xing LIANG
Author Information
1. 青岛市市立医院口腔科
- Keywords:
Nickel;
Chromium alloys;
Urinalysis;
Serologic tests
- From:
Chinese Journal of Stomatology
2012;47(z1):158-161
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical application safety of nickel-chromium alloy in porcelain-fused-to-metal (PFM) restoration by assessment of nickel and chromium levels in human urine and serum before and after the removal of the restoration.Methods Eighty-six patients were recruited in the study.They were those who suspected that nickel-chromium alloy PFM might affect their health and therefore came to hospital to ask for removal of prosthesis.The nickel and chromium levels in urine of these patients were examined before and after removal the nickel-chromium alloy PFM restoration.At the same time,sixty nine of these 86 patients also underwent blood test to exam the serum nickel and chromium levels before and after the removal of the nickel-chromium alloy PFM restorations.In addition,the urinary nickel and chromium levels in these patients were also analyzed according to their age,gender,the number and duration of PFM restorations,and the extent of metal exposure in their restoration.Results The urinary nickel levels before and after removal of the nickel-chromium alloy PFM restoration in 86 patients were (3.52 ±3.05) μg/L and (3.31 ± 3.28) μg/L respectively.The urinary chromium levels before and after removal of the nickel-chromium alloy PFM restoration were (0.81 ± 0.54) μg/L and (1.34 ± 1.15) μg/Lrespectively.The serum nickel levels before and after removal of the nickel-chromium alloy PFM restoration in 69 patients were (2.04 ± 1.06) μg/L and (2.67 ± 2.32) μg/L respectively.The serum chromium levels before and after removal of the nickel-c hromium alloy PFM restoration were (1.07 ± 0.88) μg/L and (1.02 ± 0.86) μg/L respectively.There were no statistical difference between the results of the urinary and serum nickel and chromfium levels in patients before and after removal of the nickel-chromium alloy PFM restoration(P ＞ 0.05).Conclusions The amount of nickel and chromium released from nickel-chromium alloy PFM restoration is negligible,which would not affect the urine and serum levels of nickel and chromium in human.
