Morbidity of oral lesions related to human herpesvirus in HIV-infected patients from Yunnan China
10.3760/cma.j.issn.1002-0098.2012.s1.026
- VernacularTitle:云南地区HIV感染者疱疹病毒相关口腔损害发病情况分析
- Author:
Hui-Ping SHI
1
;
Wen SHU
;
Rong LI
;
Chong-Xi LI
;
Jin-Song BAI
;
Kai-Wen DUAN
Author Information
1. 650051,昆明医科大学附属延安医院·昆明市延安医院口腔科
- Keywords:
Human immunodeficiency virus proteins;
Mouth mucosa;
Human herpesvirus;
CD4 lymphocytes
- From:
Chinese Journal of Stomatology
2012;47(z1):113-117
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the morbidity of oral lesions related to human herpesvirus among a group of HIV-infected patients and its relationship with CD4.Methods A cross-sectional study was conducted in the 992 HIV-infected patients who did not receive highly active anti-retroviral therapy (HAART) in Yunnan area.Oral examination were performed by 4 dentists.Counts of CD4 + and other data were collected and statistically analyzed.Results Of the 992 cases,209 (21.1％) cases with oral lesions related to human herpesvirus were found.The virus-related diseases included herpes simplex virus (HSV) infection (10.8％,107/992),herps zoster (0.7％,7/992),oral hairy leukoplakia (OHL) (9.1％,90/992),recurrent aphthous ulcer (RAU) (9.3 ％,92/992) and Kaposi sarcoma (KS) (0.5 ％,5/992).There was a correlation between CD4 + counts and incidence of HSV infection,OHL and RAU.Oral hepes zoster had no correlation with CD4 counts.Conclusions Oral lesions associated with human herpesvirus were very common in Yunnan HIV-infected people.Among them,incidence of HSV infection,RAU and OHL was most frequently seen.
