In vitro study on the effect of the composite of propolis and magnolol on the growth of Streptococcus mutans
10.3760/cma.j.issn.1002-0098.2012.s1.016
- VernacularTitle:蜂胶与厚朴酚混合物抑制变形链球菌生长的体外研究
- Author:
Guang-Jie BAO
1
;
Qiu-Shuang GAO
;
Shuang-Sheng HUANG
;
Man-Li GUO
Author Information
1. 西北民族大学口腔医学国家民委重点实验室
- Keywords:
Propolis;
Streptococcus mutans;
Microbial sensitivity tests;
Magnolol
- From:
Chinese Journal of Stomatology
2012;47(z1):74-76
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of the composite of propolis and magnolol on the growth of Streptococcus mutans (Sm).Methods The solution concentration of the propolis (250,125,62.5,31.25,15.625 g/L),magnolol (0.0625,0.0313,0.0156,0.0078,0.0039 g/L) and the composite of those two (propolis,magnolol) A1 (250 g/L,0.0625 g/L),A2(125 g/L,0.0313 g/L),A3 (62.5 g/L,0.0156 g/L),A4 (31.25 g/L,0.0078 g/L),A5 (15.625 g/L,0.0039 g/L) were chosen according to pretested minimum inhibitory concentration (MIC).The solutions were proportionally diluted to the presupposed concentration before operated on the Sm.Meanwhile,the solvent and the bacterial were also operated on the Sm as controls.Slip diffusion method was adopted to measure the inhibitory effect of those solutions on Sm.Results Bacteria inhibition zones were appeared at the concentration of 62.5 g/L prololis and 0.0156 g/L magnolol respectively.A inhibition zone appeared at the lower concentration of A5 (15.625 g/L,0.0039 g/L) of the propolis and magnolol composite.As general,the inhibition effects increased with concentration.The difference were statistically significant,P ＜ 0.05.Conclusions The inhibitory effect of the composite of propolis and magnolol would be much stronger than either of those two separately.
