Magnetic Resonance Imaging (MRI) of a Hypertrophy of Cartilage and Simultaneous Regeneration of a Damaged Meniscus after Autologous Bone Marrow Aspirates Concentrate (BMAC) Transplantation: a Case Report and Literature Review.
10.13104/imri.2017.21.3.187
- Author:
Sung Hwan BAE
1
;
Hyun joo KIM
;
Eunsun OH
;
Jiyoung HWANG
;
Seong Sook HONG
;
Jung Hwa HWANG
Author Information
1. Department of Radiology, Soonchunhyang University Hospital, Seoul, Korea. reonora@schmc.ac.kr
- Publication Type:Case Report
- Keywords:
Magnetic resonance imaging;
Bone marrow aspirate concentrate;
Cartilage regeneration;
Meniscus regeneration;
Osteoarthritis
- MeSH:
Animals;
Arthroscopy;
Bone Marrow*;
Cartilage*;
Cell Lineage;
Horns;
Humans;
Hypertrophy*;
Magnetic Resonance Imaging*;
Menisci, Tibial;
Mesenchymal Stromal Cells;
Osteoarthritis;
Regeneration*
- From:Investigative Magnetic Resonance Imaging
2017;21(3):187-191
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bone marrow aspirates concentrate (BMAC) transplantation is a well-known technique for cartilage regeneration with good clinical outcomes for symptoms in patients with osteoarthritis (OA). Magnetic resonance imaging (MRI) has an important role in evaluating the degree of cartilage repair in cartilage regeneration therapy instead of a second assessment via an arthroscopy. We experienced a case of hypertrophic regeneration of the cartilage and a presumed simultaneous regeneration of the posterior horn of the lateral meniscus after BMAC transplantation for a cartilage defect at the lateral tibial and femoral condyle. This report provides the details of a case of an unusual treatment response after a BMAC transplant. This report is the first of its kind to demonstrate a MR image that displays the simultaneous regeneration of the cartilage and meniscus with a differentiation ability of the mesenchymal stem cell to the desired cell lineage.