Phvsico-chemical propties and in vitro cell compatibilitv of a novel root-end filling material
10.3760/cma.j.issn.1002-0098.2011.s1.018
- VernacularTitle:一种新型根尖充填材料的理化性能及细胞相容性研究
- Author:
Yao-Zhong CHEN
1
;
Xiao-Ying L（U）
;
Gen-Di LIU
Author Information
1. 东南大学附属中大医院
- Keywords:
Root canal filling material;
Hydroxyapatites;
Polyacrylate;
Cell compatibility;
Tetracalcium phosphate
- From:
Chinese Journal of Stomatology
2011;46(z1):75-79
- CountryChina
- Language:Chinese
-
Abstract:
Objective To prepare a novel root end filling material and determine its physical and chemical properties and cell compatibility.Methods Samples of the novel root end filling material were developed with hydroxyapatite,tetracalcium phosphate,polyacrylic acid,citric acid and sodium citrate.Chemical composition of the new material was analyzed by Fourier transform infrared spectrophotometer (FTIR) and X-ray diffraction (XRD).Physical properties such as the setting time and compressive strength of the material were also investigated.The cytocompatibility was tested by MTT assay and direct contact assay.Results The novel root end filling material was primarily composed of HA,calcium carboxylate and calcium citrate.Its setting time was 8.77 ± 0.64 min and the compressive strength was ( 28.87 ± 3.88 )MPa at 1 day.The cytotoxicity scores of it in the serial dilution extract and different culture time ranked from grade 0 to Ⅰ.L 929 cells adhered on its surface and proliferated well.Conclusions With good physicalchemical properties and good cell compatibility,the novel root canal filling material presents a good clinical application prospect.
