Study of correlation between lichen planus' Chinese medicine differentiations and immunity
10.3760/cma.j.issn.1002-0098.2011.s1.015
- VernacularTitle:口腔扁平苔藓患者中医证型与免疫状态的相关研究
- Author:
Guo-Cheng MEI
1
;
Li-Su PENG
;
Jing LIU
;
Hong-Mei ZHOU
;
Su-Hua GUO
;
Mei LIN
Author Information
1. 四川大学华西口腔医学院
- Keywords:
Lichen planus,oral;
Immunity;
Traditional Chinese medical differentiation
- From:
Chinese Journal of Stomatology
2011;46(z1):61-64
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between traditional Chinese medical differentiation and immunity by observing the immunity of different types of lichen planus(OLP) patients and to proffer a new way of thinking on how to clinically identify the immune state of the patients.Methods Seventy cases of OLP patients were included,who were grouped into the type of accumulated heat of both heart and spleen,the type of hyperactivity of liver-fire,the type of flaring up of deficient fire and the type of deficiency of both qi and blood respectively.All patients received immune-examination,and the data were statistically analyzed.Results In OLP patients the type of flaring up of deficient fire accounted for the majority[53％ (37/70) ].The peripheral blood cells of the OLP patients generally expressed less CD-3 and CD-4 than normal[76％ (53/70) and 63％ (44/70) of the normal respectively,P ＜ 0.05 ].CD-3 (55.44 ± 5.57 ) and CD-8 ( 15.60 ± 3.93 ) were remarkably lower in the group of accumulated heat of both heart and spleen whereas CD-4/CD-8 (2.40 ± 0.69) and IgM (2279.33 ±729.23) went up.CD-4(30.52 ±7.50) in the group of flaring up of deficient fire decreased notably,and IgA (2608.7 ± 728.59) went up ( P ＜ 0.05).CD-3 (56.10 ± 3.24 ) in the group of deficiency of qi and blood went down remarkably.Conclusions The overall immune state of the OLP patients shows that the cell immunity is primarily out of order.The immune states of the OLP patients in different traditional Chinese medical types remain to a certain extent different.
