Comparison of GCF biochemical components changes during orthodontic tooth movement between children and adults

VernacularTitle:儿童与成人正畸加力前后龈沟液中生化成分的比较
Author: Ding ZHANG ¹ ; Yijin REN
Author Information

1. 北京大学
From: Chinese Journal of Stomatology 2001;36(3):219-221
CountryChina
Language:Chinese
Abstract: Objective To study the changes of biochemical components in GCF between children and adults during orthodontic tooth movement .Methods 84 patients(child group:43 subjects,adult group:41subjects)were included,each having one treatment tooth and one contralateral control tooth.The levels of PGE2,IL-6 and GM-CSF in GCF of upper lateral incisor were investigated befoe activation and at 24th hour after the applying of labial orthodontic force,by using of highly sensitive radioimmunoassay.Results PGE2,IL-6 and GM-CSF were highly detectable in GCf(>90%).At experimental sides,total amount of GCF PGE2,IL-6 and GM-CSF levels was significantly elevated at 24 th hour compared with that before activation in both child group and adult group.Mean concentration of PGE2 in GCF increased significntly at 24th hour in the two groups,while that of IL-6 and GM-CSF did only in child group.The levels of Pge2,IL-6 and GM-CSF in GCF remained at baseline throughout the study for the control teeth.Conclusion There were some differences of GCF cytokine changes between child and adult groups