A Case of Thrombocytopenia and Purpura Induced by Rifamnpin, Pyrazinamide, and Ciprofloxacin.
10.4046/trd.1997.44.4.930
- Author:
Hyung Dae SON
;
Chang Sun KIM
;
Mi Ran PARK
;
Ji Yung SEO
;
Nam Soo RHEU
;
Dong ll CHO
- Publication Type:Case Report
- Keywords:
Thrombocytopenia;
Purpura;
Rifampin;
Pyrazinamide;
Ciprofloxacin
- MeSH:
Ciprofloxacin*;
Female;
Humans;
Purpura*;
Pyrazinamide*;
Rifampin;
Thrombocytopenia*;
Young Adult
- From:Tuberculosis and Respiratory Diseases
1997;44(4):930-934
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Drug-induced thrombocytopenia and purpura have boon developed by many various agents. Rifampin and Pyrazinamide have been known as bactericidal antituberculous drugs, but, the above side effects have been a problem. Especially, hematologic side effects art fatal to patients occasionally. Rifampin-induced thrombocytopenia and purpura have been well known, also, pyrazinamide-induced thrombocytopenia have been reported. A new quilonone agent Ciprofloxacin, has been commonly used in clinics now, but it's side effects are not known well. So, we report a case of a 23-year-old female with thrombocytopenia and purpura after taking Rifampin, Pyrazinamide, and Ciprofloxacin as antituberculous agents.