Application of diffusion weighted imaging in accurate diagnosis of middle ear cholesteatoma
10.3760/cma.j.cn115330-20200624-00524
- VernacularTitle:磁共振弥散加权成像在中耳胆脂瘤精准诊断中的应用价值
- Author:
Fang GUO
1
;
Dejun ZHANG
;
Zeming FU
;
Yingyuan GUO
;
Yining WAN
;
Guofang GUAN
;
Junfeng LYU
;
Xiuying CHEN
Author Information
1. 吉林大学第二医院耳鼻咽喉头颈外科，长春 130041
- Keywords:
Cholesteatoma, middle ear;
Diffusion magnetic resonance imaging;
Tomography, X-Ray computed
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2020;55(11):1037-1042
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the accuracy of diffusion weighted magnetic resonance imaging (DWI-MRI) combined with high resolution temporal bone CT (HRCT) in the location diagnosis of middle ear cholesteatoma and its value in the postoperative follow-up.Methods:134 patients with inital cholesteatoma and 22 patients with suspected recurrent cholesteatoma were selected for HRCT, conventional MRI and DWI examination. Based on the intraoperative and pathological diagnosis, DWI and HRCT images were combined to evaluate the consistency between the lesion location and invasion area of the initial cholesteatoma and intraoperative lesions. The results of HRCT and DWI in the diagnosis of recurrent middle ear cholesteatoma were statistically analyzed to evaluate their diagnostic efficacy.Results:The accuracy rate of DWI combined with HRCT was 90.3%.The sensitivity, specificity, positive predictive value and negative predictive value of HRCT and DWI in the diagnosis of recurrent middle ear cholesteatoma were 27.8%, 75.0%, 83.3%, 18.8% and 100%, 75.0%, 94.7% and 100%, respectively, and the Kappa values consistent with the pathological results were 0.024 and 0.843, respectively. Chi-square test confirmed that there were differences in the diagnosis between groups ( P<0.001). Conclusions:Combined with the high sensitivity of DWI and the high resolution of HRCT, the accuracy of preoperative positioning of the newly diagnosed cholesteatoma can be improved and surgery strategy can be guided. DWI is also of high diagnostic value for recurrent cholesteatoma in the middle ear.
