Research advances in molecular mechanisms underlying the different biological behaviors of vestibular schwannoma
10.3760/cma.j.issn.1673-0860.2016.06.020
- VernacularTitle:听神经瘤不同生物学行为的分子机制研究进展
- Author:
Zhaoyan WANG
1
;
Jun YANG
;
Hao WU
Author Information
1. 200092,上海交通大学医学院附属新华医院耳鼻咽喉头颈外科上海交通大学医学院耳科学研究所上海市耳鼻疾病转化医学重点实验室
- Keywords:
Neuroma,acoustic;
Genes,Neurofibromatosis 2
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2016;51(6):473-475
- CountryChina
- Language:Chinese
-
Abstract:
Current treatment options of vestibular schwannomas should not be limited to conventional surgery because of the variability of tumor growth.Recent studies of vestibular schwannomas suggested that the development of the tumor tended to depend on the shuttle between the nucleus and cytoplasm,and the expression patterns of merlin protein.New drug targets for schwannoma therapies might be identified through future in-depth investigations of the function of merlin,thus contributing to tumor control.
