Clinical observation of traumatic granuloma after CO2 laser cordectomy and laryngopharyngeal reflux
10.3760/cma.j.issn.1673-0860.2014.05.005
- VernacularTitle:咽喉反流对 CO2激光声带切除术后创伤性肉芽肿影响的初步观察
- Author:
Liping WANG
1
;
Shishang SUN
;
Sining WANG
;
Dashuai LIANG
;
Wenyue JI
Author Information
1. 中国医科大学附属盛京医院耳鼻咽喉科
- Keywords:
Vocal cords;
Laser therapy;
Granuloma,laryngeal;
Laryngopharyngeal reflux
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2014;(5):374-378
- CountryChina
- Language:Chinese
-
Abstract:
Objective Through clinical observation of granuloma after CO 2 laser cordectomy under suspensive laryngoscope to discuss the effects of laryngopharyngeal reflux ( LPR ) to traumatic granuloma . Methods According to the classification of depth and range of CO 2 laser cordectomy , 111 cases were divided into 5 groups , and the incidence of postoperative granuloma of each group was observed .The largest number of the 5 groups was 49 cases of type Ⅲ CO2 laser cordectomy which was subdivided into 4 groups according to whether or not laryngopharyngeal reflux and whether or not proton pump inhibitor ( PPI ) treatment.Results In 111 cases, 56 cases (50.5%) developed granuloma after CO2 laser cordectomy. The incidence of traumatic granuloma after surgery was 10%(1/10), 26.1%(6/23), 53.1%(26/49), 78.6% (11/14), 80.0% (12/15) in Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ type, respectively.It had statistical significance in chi-square test between 5 kinds of operative classification and the incidences of postoperative granuloma (χ2 =20.32,P<0.01) and Spearman correlation analysis showed positive correlation between classification of operation and incidences of granuloma (r=0.44,P<0.01).According to LPR (-), LPR (+) and PPI ( +) , PPI ( -) , the incidence of granuloma had statistical significance in these 4 group patients of 49 typeⅢcases (χ2 =5.83,P<0.05).The incidence of granuloma after surgery was the lowest in LPR ( -) PPI ( +) group ( 30%) and the highest in LPR ( +) PPI ( -) group ( 80%) , and it showed significant difference (χ2 =6.25, P<0.05).Conclusions With the increase of removal depth and the range after CO 2 laser cordectomy , it appears rising trend in incidence of granuloma . Laryngopharyngeal reflux and PPI therapy on the incidence of traumatic granuloma has certain influence .
