Research status of traditional Chinese medicine monomer,drug-to-drug groups and compound formula in the treatment of endometriosis

VernacularTitle:中药单体、药对药组及复方治疗子宫内膜异位症的研究现状
Author: Bin YUE ¹ ; Yuan-Huan CHEN ; Quan-Sheng WU ; Xiao-Hua ZHANG ; Yuan CHENG ; Hao MEI ; Can-Can HUANG ; Zuo-Liang ZHANG ; Xiu-Jia JI
Author Information

1. 甘肃中医药大学中医临床学院,甘肃兰州 730000
Keywords: traditional Chinese medcine monomer; drug-to-drug group; Chinese herbal compound; endometriosis; active ingredient; signaling pathway
From: The Chinese Journal of Clinical Pharmacology 2024;40(15):2283-2287
CountryChina
Language:Chinese
Abstract: Interventions for endometriosis(EMs)include surgical excision of lesions and hormonal therapy,which usually have limited efficacy and adverse drug reactions.Traditional Chinese medicine(TCM)has the multi-component and multi-target characteristics,which can help patients achieve good clinical benefits by intervening in different parts of the disease.In this paper,we briefly discuss the modern pharmacology of Sanlang and Curcuma longa,and deeply summarize the possible mechanisms of action of TCM monomer and classical compound extracts and their active ingredients through signal pathways in inflammation,immune system,angiogenesis,hormone regulation,etc.,so as to provide theoretical bases for the clinical use of TCM monomers,drug-to-drug groups and compounds in the treatment of EMs.