10 Cases of Paradoxical Expansion of Intracranial Terculomas During Chemotherapy.
10.4046/trd.2001.51.3.260
- Author:
Yangki MINN
- Publication Type:Case Report
- Keywords:
Tuberculosis;
Tuberculoma;
Paradoxical;
CSF(cerebrospinal fluid)
- MeSH:
Brain;
Drug Therapy*;
Humans;
Tuberculoma;
Tuberculoma, Intracranial;
Tuberculosis
- From:Tuberculosis and Respiratory Diseases
2001;51(3):260-264
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Paradoxical intracranial tuberculoma is tuberculoma that developed or was enlarged during antituberculous therapy. The course of the disease or effective treatment are not well known. METHOD: Patients who developed intracranial tuberculoma or an enlarged tuberculoma during antituberculous therapy were investigated. Ten patients were enrolled. RESULTS: Paradoxical intracranial tuberculoma was detected 67.9 days after antituberculous therapy. The symptoms worsened over a period of 102.3 days. Improvement was noted after 165.4 days. Four patients recovered on the brain image and 4 recovered clinically. The CSF findings showed that the paradoxical tuberculomas had developed or were aggravated, the CSF findings was aggravated. CONCLUSION: Paradoxical intracranial tuberculoma can develop without specific symptoms. Paradoxical intracranial tuberculoma may not be a paradoxical response and may be a natural course of intracranial tuberculosis or a natural response to antituberculous therapy.
